Summary: In accordance with OECD Test Guideline No. 408 at a GLP-compliant testing facility, the study revealed that no signs of changed survival data, body weight, diet or water consumption, blood count or biochemical parameters, macroscopic or microscopic changes in organs could be detected at concentrations of 0.66 mg/kg bw/day (10 animals). Furthermore, no signs of toxicity could be found.
Categorisation according to Klimisch et al. 1997: "reliable without restriction"
The following price (net) is requested by the study owner: 60 000€ (incl. Test ID 703: Comet Assay/CBD and Test ID 704: BRMT-Test/CBD) (please note: This is the price the study owner is asking for the study)
Summary: In accordance with OECD Test Guideline No. 408 (incl. OECD Test Guideline No. 489) at a GLP-compliant testing facility, the study revealed no changes in survival data and no changes in water or diet consumption. However, toxicity was observed through signs of oxidative stress at concentrations of 0.66 mg/kg/day and 1.33 mg/kg bw/day. No single-dose pharmacokinetic study was conducted. No genotoxic potential was detected in blood samples or liver cells.
Categorisation according to Klimisch et al. 1997: "reliable without restriction"
The following price (net) is requested by the study owner: 55 000€