Summary: The test substance was evaluated following OECD Test Guideline No. 487 at a testing facility that is certified for Good Laboratory Practice (GLP). No genotoxic effects were detected in human peripheral blood lymphocytes after short-term exposure, with or without metabolic activation, at concentrations of 30, 35, 40, 45, 50, 55, and 60 µg/ml. The outcome of the micronucleus test extended exposure for 24h without metabolic activation was negative, too. The results indicate that the tested substance does not cause chromosome breaks and/or result in chromosome gain or loss in this testing system.
Categorisation according to Klimisch et al. 1997: "reliable without restriction"
The following price (net) is requested by the study owner: 15 000€